4OBV
Ruminococcus gnavus tryptophan decarboxylase RUMGNA_01526 (alpha-FMT)
Summary for 4OBV
Entry DOI | 10.2210/pdb4obv/pdb |
Related | 4OBU |
Descriptor | Pyridoxal-dependent decarboxylase domain protein, alpha-(fluoromethyl)-D-tryptophan, {5-hydroxy-4-[(1E)-4-(1H-indol-3-yl)-3-oxobut-1-en-1-yl]-6-methylpyridin-3-yl}methyl dihydrogen phosphate (3 entities in total) |
Functional Keywords | type 1 plp-dependent, decarboxylase, lyase |
Biological source | Ruminococcus gnavus |
Total number of polymer chains | 4 |
Total formula weight | 222652.80 |
Authors | Fraser, J.S.,Van Benschoten, A.H. (deposition date: 2014-01-07, release date: 2014-10-29, Last modification date: 2024-02-28) |
Primary citation | Williams, B.B.,Van Benschoten, A.H.,Cimermancic, P.,Donia, M.S.,Zimmermann, M.,Taketani, M.,Ishihara, A.,Kashyap, P.C.,Fraser, J.S.,Fischbach, M.A. Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine. Cell Host Microbe, 16:495-503, 2014 Cited by PubMed: 25263219DOI: 10.1016/j.chom.2014.09.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
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