4O9U
Mechanism of transhydrogenase coupling proton translocation and hydride transfer
Summary for 4O9U
Entry DOI | 10.2210/pdb4o9u/pdb |
Descriptor | NAD(P) transhydrogenase subunit alpha 2, NAD(P) transhydrogenase subunit beta, NAD/NADP transhydrogenase alpha subunit 1, ... (5 entities in total) |
Functional Keywords | nicotinamide nucleotide transhydrogenase, couples proton motive, hydride transfer, holo-transhydrogease from thermus thermophilus assembled from subunits alpha1, alpha2, truncated beta, and domain iii as a dimer, respiratory proton pump enzyme forming cytosolic nadp(h), protons and nad(h), nadp(h), proton translocation and hydride transfer, periplasmic membrane and cytosol, membrane protein |
Biological source | Thermus thermophilus More |
Total number of polymer chains | 6 |
Total formula weight | 201374.27 |
Authors | Leung, J.H.,Yamaguchi, M.,Moeller, A.,Schurig-Briccio, L.A.,Gennis, R.B.,Potter, C.S.,Carragher, B.,Stout, C.D. (deposition date: 2014-01-02, release date: 2015-01-28, Last modification date: 2024-03-13) |
Primary citation | Leung, J.H.,Schurig-Briccio, L.A.,Yamaguchi, M.,Moeller, A.,Speir, J.A.,Gennis, R.B.,Stout, C.D. Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer. Science, 347:178-181, 2015 Cited by PubMed: 25574024DOI: 10.1126/science.1260451 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (6.926 Å) |
Structure validation
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