4O7X
Crystal structure of human ALKBH5 in complex with Mn2+
Summary for 4O7X
Entry DOI | 10.2210/pdb4o7x/pdb |
Descriptor | RNA demethylase ALKBH5, MANGANESE (II) ION (3 entities in total) |
Functional Keywords | 6-methyl adenosine, protein/dna interaction, human dioxygenase, metal-binding, nucleus, demethylation, rna repair, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus speckle : Q6P6C2 |
Total number of polymer chains | 1 |
Total formula weight | 26440.06 |
Authors | |
Primary citation | Feng, C.,Liu, Y.,Wang, G.,Deng, Z.,Zhang, Q.,Wu, W.,Tong, Y.,Cheng, C.,Chen, Z. Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition J.Biol.Chem., 289:11571-11583, 2014 Cited by PubMed: 24616105DOI: 10.1074/jbc.M113.546168 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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