4O6L

Crystal Structure of TTK kinase domain with an inhibitor: 401498 (N-[(1R)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1H-indazole-5-carboxamide)

4O6L の概要

• エントリーDOI: 10.2210/pdb4o6l/pdb
• 分子名称: Dual specificity protein kinase TTK, N-[(1R)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1H-indazole-5-carboxamide, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: kinase, ttk, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 66588.73

構造登録者

Qiu, W.,Plotnikova, O.,Feher, M.,Awrey, D.E.,Chirgadze, N.Y. (登録日: 2013-12-22, 公開日: 2014-12-24)

• 主引用文献: Qiu, W.,Plotnikova, O.,Feher, M.,Awrey, D.E.,Chirgadze, N.Y.; Crystal Structure of TTK kinase domain with an inhibitor: 401498; TO BE PUBLISHED,

実験手法

X-RAY DIFFRACTION (2.38 Å)