4O6F
Structural Basis of Estrogen Receptor Alpha Methylation Mediated by Histone Methyltransferase SmyD2
Summary for 4O6F
Entry DOI | 10.2210/pdb4o6f/pdb |
Descriptor | N-lysine methyltransferase SMYD2, Estrogen receptor, ZINC ION, ... (7 entities in total) |
Functional Keywords | histone methyltransferase, smyd2, estrogen receptor er alpha, methylation, estrogen signaling, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytosol (By similarity): Q9NRG4 Isoform 1: Nucleus. Isoform 3: Nucleus. Nucleus: P03372 |
Total number of polymer chains | 2 |
Total formula weight | 52273.31 |
Authors | Jiang, Y.,Trescott, L.,Holcomb, J.,Brunzelle, J.,Sirinupong, N.,Shi, X.,Yang, Z. (deposition date: 2013-12-20, release date: 2014-03-26, Last modification date: 2023-09-20) |
Primary citation | Jiang, Y.,Trescott, L.,Holcomb, J.,Zhang, X.,Brunzelle, J.,Sirinupong, N.,Shi, X.,Yang, Z. Structural Insights into Estrogen Receptor alpha Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation. J.Mol.Biol., 426:3413-3425, 2014 Cited by PubMed: 24594358DOI: 10.1016/j.jmb.2014.02.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.822 Å) |
Structure validation
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