4O2Z

Crystal Structure of MPK3 from Leishmania donovani, LdBPK_100540 in the presence of NVP-BBT594

Summary for 4O2Z

• Entry DOI: 10.2210/pdb4o2z/pdb
• Descriptor: Mitogen-activated protein kinase 3, putative, 5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-2,3-dihydro-1H-indole-1-carboxamide (3 entities in total)
• Functional Keywords: neglected disease, structural genomics, structural genomics consortium, sgc, kinase, transferase
• Biological source: Leishmania donovani
• Total number of polymer chains: 1
• Total formula weight: 43789.98

Authors

Wernimont, A.K.,Walker, J.R.,Hutchinson, A.,Loppnau, P.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Hui, R.,Mangos, M.,Structural Genomics Consortium (SGC) (deposition date: 2013-12-17, release date: 2014-01-22, Last modification date: 2023-09-20)

• Primary citation: Wernimont, A.K.,Walker, J.R.,Hutchinson, A.,Loppnau, P.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Hui, R.,Mangos, M.,Structural Genomics Consortium (SGC); Crystal Structure of MPK3 from Leishmania donovani, LdBPK_100540 in the presence of NVP-BBT594; To be Published,

Experimental method

X-RAY DIFFRACTION (2.71 Å)