4NZW

Crystal Structure of STK25-MO25 Complex

Summary for 4NZW

• Entry DOI: 10.2210/pdb4nzw/pdb
• Descriptor: Calcium-binding protein 39, Serine/threonine-protein kinase 25, 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE (3 entities in total)
• Functional Keywords: scafolding protein, ser/thr protein kinase, transferase activator-transferase complex, transferase activator/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : Q9Y376 O00506
• Total number of polymer chains: 2
• Total formula weight: 72785.13

Authors

Feng, M.,Hao, Q.,Zhou, Z.C. (deposition date: 2013-12-13, release date: 2014-12-03, Last modification date: 2023-11-08)

• Primary citation: Hao, Q.,Feng, M.,Shi, Z.,Li, C.,Chen, M.,Wang, W.,Zhang, M.,Jiao, S.,Zhou, Z.; Structural insights into regulatory mechanisms of MO25-mediated kinase activation.; J.Struct.Biol., 186:224-233, 2014; PubMed: 24746913; DOI: 10.1016/j.jsb.2014.04.005

Experimental method

X-RAY DIFFRACTION (3.583 Å)