4NZR
Crystal structure of the antibody-binding region of Protein M (Protein M TD) in complex with anti-HIV antibody PGT135 Fab
Summary for 4NZR
Entry DOI | 10.2210/pdb4nzr/pdb |
Related | 4JM4 4NZT 4NZU |
Descriptor | PGT135 heavy chain, PGT135 light chain, Protein M TD, ... (5 entities in total) |
Functional Keywords | leucine-rich repeat, broad antibody-binding, block antibody-antigen union, variable region, immune system-protein binding complex, immune system/protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass membrane protein (Potential): P47523 |
Total number of polymer chains | 3 |
Total formula weight | 96245.84 |
Authors | Zhu, X.,Wilson, I.A. (deposition date: 2013-12-12, release date: 2014-02-19, Last modification date: 2023-09-20) |
Primary citation | Grover, R.K.,Zhu, X.,Nieusma, T.,Jones, T.,Boero, I.,MacLeod, A.S.,Mark, A.,Niessen, S.,Kim, H.J.,Kong, L.,Assad-Garcia, N.,Kwon, K.,Chesi, M.,Smider, V.V.,Salomon, D.R.,Jelinek, D.F.,Kyle, R.A.,Pyles, R.B.,Glass, J.I.,Ward, A.B.,Wilson, I.A.,Lerner, R.A. A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science, 343:656-661, 2014 Cited by PubMed: 24503852DOI: 10.1126/science.1246135 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
Download full validation report