4NZ9

Crystal Structure of FabI from S. aureus in complex with a novel benzimidazole inhibitor

Summary for 4NZ9

• Entry DOI: 10.2210/pdb4nz9/pdb
• Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADPH], 1-(4-methoxy-3-methylbenzyl)-5,6,7,8-tetrahydro-1H-naphtho[2,3-d]imidazole, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• Functional Keywords: rossman fold, reductase, nadph, reduction, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Staphylococcus aureus
• Total number of polymer chains: 2
• Total formula weight: 63238.91

Authors

Mehboob, S.,Johnson, M.E.,Santarsiero, B.D. (deposition date: 2013-12-11, release date: 2014-12-31, Last modification date: 2023-09-20)

• Primary citation: Mehboob, S.,Truong, L.,Santarsiero, B.D.,Johnson, M.E.; To be published; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)