4NTO

Crystal structure of D60A mutant of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with C2 ceramide-1-phosphate (d18:1/2:0) at 2.15 Angstrom resolution

4NTO の概要

• エントリーDOI: 10.2210/pdb4nto/pdb
• 関連するPDBエントリー: 4NT1 4NT2 4NTG 4NTI
• 分子名称: accelerated-cell-death 11, (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• 機能のキーワード: protein-lipid complexes, pi-bulge, gltp-fold, lipid transfer protein, cell death, ceramide-1-phosphate, c1p, transport protein
• 由来する生物種: Arabidopsis thaliana (mouse-ear cress)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 71001.70

構造登録者

Simanshu, D.K.,Brown, R.E.,Patel, D.J. (登録日: 2013-12-02, 公開日: 2014-02-05, 最終更新日: 2023-09-20)

• 主引用文献: Simanshu, D.K.,Zhai, X.,Munch, D.,Hofius, D.,Markham, J.E.,Bielawski, J.,Bielawska, A.,Malinina, L.,Molotkovsky, J.G.,Mundy, J.W.,Patel, D.J.,Brown, R.E.; Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.; Cell Rep, 6:388-399, 2014; PubMed: 24412362; DOI: 10.1016/j.celrep.2013.12.023

実験手法

X-RAY DIFFRACTION (2.152 Å)