4NTK

QueD from E. coli

Summary for 4NTK

• Entry DOI: 10.2210/pdb4ntk/pdb
• Related: 4NTM 4NTN
• Descriptor: 6-carboxy-5,6,7,8-tetrahydropterin synthase, ZINC ION, 2-amino-6-[(1Z)-1,2-dihydroxyprop-1-en-1-yl]-7,8-dihydropteridin-4(3H)-one, ... (5 entities in total)
• Functional Keywords: t-fold, 6-ptps, queuosine biosynthesis enzyme, sepiapterin, c27a, lyase
• Biological source: Escherichia coli
• Total number of polymer chains: 6
• Total formula weight: 84675.86

Authors

Bandarian, V.,Roberts, S.A.,Miles, Z.D. (deposition date: 2013-12-02, release date: 2014-07-16, Last modification date: 2024-02-28)

• Primary citation: Miles, Z.D.,Roberts, S.A.,McCarty, R.M.,Bandarian, V.; Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.; J.Biol.Chem., 289:23641-23652, 2014; PubMed: 24990950; DOI: 10.1074/jbc.M114.555680

Experimental method

X-RAY DIFFRACTION (1.6 Å)