4NT2

Crystal structure of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with lyso-sphingomyelin (d18:1) at 2.4 Angstrom resolution

4NT2 の概要

• エントリーDOI: 10.2210/pdb4nt2/pdb
• 関連するPDBエントリー: 4NT1 4NTG 4NTI 4NTO
• 分子名称: accelerated-cell-death 11, 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: protein-lipid complexes, gltp-fold, lipid transfer protein, cell death, lysosm, lysosphingomyelin, ceramide-1-phosphate, c1p, transport protein
• 由来する生物種: Arabidopsis thaliana (mouse-ear cress)
• 細胞内の位置: Cytoplasm : O64587
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24333.18

構造登録者

Simanshu, D.K.,Brown, R.E.,Patel, D.J. (登録日: 2013-11-29, 公開日: 2014-02-05, 最終更新日: 2023-09-20)

• 主引用文献: Simanshu, D.K.,Zhai, X.,Munch, D.,Hofius, D.,Markham, J.E.,Bielawski, J.,Bielawska, A.,Malinina, L.,Molotkovsky, J.G.,Mundy, J.W.,Patel, D.J.,Brown, R.E.; Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels.; Cell Rep, 6:388-399, 2014; PubMed: 24412362; DOI: 10.1016/j.celrep.2013.12.023

実験手法

X-RAY DIFFRACTION (2.403 Å)