4NT2
Crystal structure of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with lyso-sphingomyelin (d18:1) at 2.4 Angstrom resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006869 | biological_process | lipid transport |
| A | 0008289 | molecular_function | lipid binding |
| A | 0009751 | biological_process | response to salicylic acid |
| A | 0015914 | biological_process | phospholipid transport |
| A | 0035627 | biological_process | ceramide transport |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0120009 | biological_process | intermembrane lipid transfer |
| A | 0120013 | molecular_function | lipid transfer activity |
| A | 0120014 | molecular_function | phospholipid transfer activity |
| A | 0120016 | molecular_function | sphingolipid transfer activity |
| A | 0140338 | molecular_function | sphingomyelin transfer activity |
| A | 1902387 | molecular_function | ceramide 1-phosphate binding |
| A | 1902388 | molecular_function | ceramide 1-phosphate transfer activity |
| A | 1902389 | biological_process | ceramide 1-phosphate transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SPU A 301 |
| Chain | Residue |
| A | ASP60 |
| A | HIS143 |
| A | GLY144 |
| A | ILE147 |
| A | LEU153 |
| A | SPU302 |
| A | SO4307 |
| A | HOH426 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SPU A 302 |
| Chain | Residue |
| A | ILE147 |
| A | LYS149 |
| A | TYR156 |
| A | SPU301 |
| A | SO4304 |
| A | SO4307 |
| A | TRP145 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | LYS64 |
| A | ARG99 |
| A | ARG103 |
| A | HOH475 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | ARG148 |
| A | LYS149 |
| A | SPU302 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 305 |
| Chain | Residue |
| A | SER181 |
| A | ASN184 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 306 |
| Chain | Residue |
| A | ARG11 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 307 |
| Chain | Residue |
| A | TRP145 |
| A | ARG148 |
| A | SPU301 |
| A | SPU302 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 308 |
| Chain | Residue |
| A | ILE52 |
| A | ALA53 |
| A | PHE54 |
| A | LYS55 |
| A | PHE56 |
| A | VAL151 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 309 |
| Chain | Residue |
| A | VAL79 |
| A | ASP83 |
| A | LEU196 |
| A | LYS200 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24412362","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
