4NS0
The C2A domain of Rabphilin 3A in complex with PI(4,5)P2
Summary for 4NS0
Entry DOI | 10.2210/pdb4ns0/pdb |
Related | 4LT7 4NP9 |
Descriptor | Rabphilin-3A, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, SULFATE ION, ... (4 entities in total) |
Functional Keywords | c2 domain, calcium binding, phospholipid binding, rabphilin-3a, c2a, synaptic exocytosis metal-binding, protein transport, c-2 domain fold, exophilin-1 |
Biological source | Rattus norvegicus (brown rat,rat,rats) |
Cellular location | Cell junction, synapse (By similarity): P47709 |
Total number of polymer chains | 1 |
Total formula weight | 16148.11 |
Authors | Guillen, J.,Ferrer-Orta, C.,Buxaderas, M.,Perez-sanchez, D.,Guerrero-Valero, M.,Luengo-Gil, G.,Pous, J.,Guerra, P.,Gomez-Fernandez, J.C.,Verdaguer, N.,Corbalan-Garcia, S. (deposition date: 2013-11-27, release date: 2013-12-25, Last modification date: 2023-11-08) |
Primary citation | Guillen, J.,Ferrer-Orta, C.,Buxaderas, M.,Perez-Sanchez, D.,Guerrero-Valero, M.,Luengo-Gil, G.,Pous, J.,Guerra, P.,Gomez-Fernandez, J.C.,Verdaguer, N.,Corbalan-Garcia, S. Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc.Natl.Acad.Sci.USA, 110:20503-20508, 2013 Cited by PubMed: 24302762DOI: 10.1073/pnas.1316179110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report