4NRM

Crystal structure of human ALKBH5 in complex with citrate and acetate

Summary for 4NRM

Entry DOI	10.2210/pdb4nrm/pdb
Related	4NRO 4NRP 4NRQ
Descriptor	RNA demethylase ALKBH5, CITRATE ANION, ACETATE ION, ... (4 entities in total)
Functional Keywords	alkbh5, 6-methyl adenosine, protein/dna interaction, human dioxygenase, metal-binding, oxidoreductase, demethylation, rna repair
Biological source	Homo sapiens (human)
Cellular location	Nucleus speckle : Q6P6C2
Total number of polymer chains	1
Total formula weight	26633.27
Authors	Feng, C.,Chen, Z.,Liu, Y. (deposition date: 2013-11-27, release date: 2014-03-19, Last modification date: 2023-11-08)
Primary citation	Feng, C.,Liu, Y.,Wang, G.,Deng, Z.,Zhang, Q.,Wu, W.,Tong, Y.,Cheng, C.,Chen, Z. Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition J.Biol.Chem., 289:11571-11583, 2014 Cited by PubMed: 24616105 DOI: 10.1074/jbc.M113.546168 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.17 Å)

Structure validation