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4NRM

Crystal structure of human ALKBH5 in complex with citrate and acetate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RNA demethylase ALKBH5polymer23026385.11UniProt (Q6P6C2)
Pfam (PF13532)
Homo sapiens (human)Alkylated DNA repair protein alkB homolog 5, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5
2B
(A)
CITRATE ANIONnon-polymer189.11Chemie (FLC)
3C
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
4D
(A)
waterwater18.066Chemie (HOH)
Sequence modifications
A: 66 - 292 (UniProt: Q6P6C2)
PDBExternal DatabaseDetails
Gly 63-expression tag
His 64-expression tag
Met 65-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26385.1
Non-Polymers*Number of molecules2
Total formula weight248.1
All*Total formula weight26633.3
*Water molecules are not included.

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PDB entries from 2025-12-24

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