4NR1

Factor inhibiting HIF-1 alpha in complex with consensus ankyrin repeat domain-(d)allyl-GLY peptide

4NR1 の概要

• エントリーDOI: 10.2210/pdb4nr1/pdb
• 関連するPDBエントリー: 4JAA
• 分子名称: Hypoxia-inducible factor 1-alpha inhibitor, CONSENSUS ANKYRIN REPEAT DOMAIN-(D)allyl glycine, ZINC ION, ... (6 entities in total)
• 機能のキーワード: on-heme, dioxygenase, oxygenase, dna-binding, metal-binding, transcription, helix-loop-helix-beta, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, epigenetic regulation, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: Q9NWT6
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43326.78

構造登録者

Scotti, J.S.,McDonough, M.A.,Schofield, C.J. (登録日: 2013-11-26, 公開日: 2015-01-21, 最終更新日: 2023-12-06)

• 主引用文献: Scotti, J.S.; Structure of an oxygenase in complex with substrate; To be Published,

実験手法

X-RAY DIFFRACTION (2.68 Å)