4NQ1

Legionella pneumophila dihydrodipicolinate synthase with first substrate pyruvate bound in the active site

4NQ1 の概要

• エントリーDOI: 10.2210/pdb4nq1/pdb
• 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: tim barrel, lysine biosynthesis, dihydrodipicolinate synthesis, pyruvate, lyase
• 由来する生物種: Legionella pneumophila
• 細胞内の位置: Cytoplasm (By similarity): D5T7I7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63944.66

構造登録者

Siddiqui, T.,Paxman, J.J. (登録日: 2013-11-23, 公開日: 2014-01-01, 最終更新日: 2023-11-29)

• 主引用文献: Siddiqui, T.,Paxman, J.J.,Dogovski, C.,Panjikar, S.,Perugini, M.A.; Legionella pneumophila DHDPS: The First Case of Non-Lysine Inhibition in a Gram-Negative Pathogen; To be Published,

実験手法

X-RAY DIFFRACTION (1.65 Å)