4NP8
Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph)
Replaces: 3FQPSummary for 4NP8
Entry DOI | 10.2210/pdb4np8/pdb |
Related | 2ON9 3OVL |
Descriptor | Microtubule-associated protein tau (2 entities in total) |
Functional Keywords | amyloid-like protofibril, protein fibril |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol: P10636 |
Total number of polymer chains | 1 |
Total formula weight | 749.92 |
Authors | Landau, M.,Eisenberg, D.,Sawaya, M.R.,Dannenberg, J.,Kobko, N. (deposition date: 2013-11-20, release date: 2013-12-18, Last modification date: 2023-09-20) |
Primary citation | Wiltzius, J.J.,Landau, M.,Nelson, R.,Sawaya, M.R.,Apostol, M.I.,Goldschmidt, L.,Soriaga, A.B.,Cascio, D.,Rajashankar, K.,Eisenberg, D. Molecular mechanisms for protein-encoded inheritance. Nat.Struct.Mol.Biol., 16:973-978, 2009 Cited by PubMed: 19684598DOI: 10.1038/nsmb.1643 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
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