4NOD
Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation
Summary for 4NOD
Entry DOI | 10.2210/pdb4nod/pdb |
Descriptor | Transcription factor A, mitochondrial, 5'-D(*TP*TP*GP*GP*GP*GP*TP*AP*TP*GP*GP*GP*GP*CP*TP*TP*GP*GP*(BRU)P*TP*GP*G)-3', 5'-D(*CP*CP*AP*AP*CP*CP*AP*AP*GP*CP*CP*CP*CP*AP*TP*AP*CP*CP*CP*CP*AP*A)-3' (3 entities in total) |
Functional Keywords | hmg, dna bending, tfb2m, mtrnap, bru substitution to hsp1, t19, transcription regulator-dna complex, transcription regulator/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Mitochondrion: Q00059 |
Total number of polymer chains | 12 |
Total formula weight | 162551.02 |
Authors | Ngo, H.B.,Lovely, G.A.,Phillips, R.,Chan, D.C. (deposition date: 2013-11-19, release date: 2014-01-22, Last modification date: 2023-09-20) |
Primary citation | Ngo, H.B.,Lovely, G.A.,Phillips, R.,Chan, D.C. Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation. Nat Commun, 5:3077-3077, 2014 Cited by PubMed: 24435062DOI: 10.1038/ncomms4077 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.897 Å) |
Structure validation
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