4NMB

Crystal structure of proline utilization A (PutA) from Geobacter sulfurreducens PCA in complex with L-lactate

Replaces:  4F9I

Summary for 4NMB

• Entry DOI: 10.2210/pdb4nmb/pdb
• Related: 4NM9 4NMA 4NMC 4NMD 4NME 4NMF
• Descriptor: Proline dehydrogenase and Delta-1-pyrroline-5-carboxylate dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, (2S)-2-HYDROXYPROPANOIC ACID, ... (5 entities in total)
• Functional Keywords: flavoenzyme, rossmann fold, aldehyde dehydrogenase, flavin adenine dinucleotide, nicotinamide adenine dinucleotide, proline catabolism, substrate channeling, bifunctional enzyme, oxidoreductase
• Biological source: Geobacter sulfurreducens
• Total number of polymer chains: 2
• Total formula weight: 226791.07

Authors

Singh, H.,Almo, S.C.,Tanner, J.J. (deposition date: 2013-11-14, release date: 2014-02-19, Last modification date: 2023-12-06)

• Primary citation: Singh, H.,Arentson, B.W.,Becker, D.F.,Tanner, J.J.; Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site.; Proc.Natl.Acad.Sci.USA, 111:3389-3394, 2014; PubMed: 24550478; DOI: 10.1073/pnas.1321621111

Experimental method

X-RAY DIFFRACTION (2.198 Å)