4NM0
Crystal structure of peptide inhibitor-free GSK-3/Axin complex
Summary for 4NM0
Entry DOI | 10.2210/pdb4nm0/pdb |
Related | 4NM3 4NM5 4NM7 4NU1 |
Descriptor | Glycogen synthase kinase-3 beta, Axin-1, GLYCEROL, ... (8 entities in total) |
Functional Keywords | wnt, lrp6, auto-inhibited, gsk-3, axin, kinase, primed substrate, transferase-peptide complex, transferase/peptide |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P49841 O15169 |
Total number of polymer chains | 2 |
Total formula weight | 48044.75 |
Authors | Chu, M.L.-H.,Stamos, J.L.,Enos, M.D.,Shah, N.,Weis, W.I. (deposition date: 2013-11-14, release date: 2014-03-26, Last modification date: 2023-09-20) |
Primary citation | Stamos, J.L.,Chu, M.L.,Enos, M.D.,Shah, N.,Weis, W.I. Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6. Elife, 3:e01998-e01998, 2014 Cited by PubMed: 24642411PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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