4NFS

V203A horse liver alcohol dehydrogenase E complexed with NAD and 2,2,2-trifluoroethanol

Summary for 4NFS

Entry DOI	10.2210/pdb4nfs/pdb
Related	1A71 1HLD 3OQ6 4DWV 4DXH 4NFH
Descriptor	Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
Functional Keywords	rossmann fold, dehydrogenase, nad, liver cytosol, oxidoreductase
Biological source	Equus caballus (domestic horse,equine)
Cellular location	Cytoplasm: P00327
Total number of polymer chains	2
Total formula weight	81911.71
Authors	Plapp, B.V. (deposition date: 2013-10-31, release date: 2013-11-13, Last modification date: 2023-09-20)
Primary citation	Yahashiri, A.,Rubach, J.K.,Plapp, B.V. Effects of cavities at the nicotinamide binding site of liver alcohol dehydrogenase on structure, dynamics and catalysis. Biochemistry, 53:881-894, 2014 Cited by PubMed: 24437493 DOI: 10.1021/bi401583f PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation