4NAL
Arabidopsis thaliana IspD in complex with tribromodichloro-pseudilin
Summary for 4NAL
Entry DOI | 10.2210/pdb4nal/pdb |
Related | 1INI 1W77 2YC5 4NAI 4NAK 4NAN |
Descriptor | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic, 2,4-DICHLORO-6-(3,4,5-TRIBROMO-1H-PYRROL-2-YL)PHENOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (6 entities in total) |
Functional Keywords | herbicide, anti-infectives, pseudilin, natural product, drug discovery, allosteric inhibition, rossmann fold, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Arabidopsis thaliana (mouse-ear cress, thale-cress) |
Cellular location | Plastid, chloroplast stroma (Probable): P69834 |
Total number of polymer chains | 1 |
Total formula weight | 26884.95 |
Authors | Kunfermann, A.,Witschel, M.,Illarionov, B.,Martin, R.,Rottmann, M.,Hoffken, H.W.,Seet, M.,Eisenreich, W.,Knolker, H.-J.,Fischer, M.,Bacher, A.,Groll, M.,Diederich, F. (deposition date: 2013-10-22, release date: 2014-01-29, Last modification date: 2023-09-20) |
Primary citation | Kunfermann, A.,Witschel, M.,Illarionov, B.,Martin, R.,Rottmann, M.,Hoffken, H.W.,Seet, M.,Eisenreich, W.,Knolker, H.J.,Fischer, M.,Bacher, A.,Groll, M.,Diederich, F. Pseudilins: Halogenated, Allosteric Inhibitors of the Non-Mevalonate Pathway Enzyme IspD. Angew.Chem.Int.Ed.Engl., 53:2235-2239, 2014 Cited by PubMed: 24446431DOI: 10.1002/anie.201309557 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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