4N8Q
Alternative substrates of Mycobacterium tuberculosis anthranilate phosphoribosyl transferase
Summary for 4N8Q
Entry DOI | 10.2210/pdb4n8q/pdb |
Related | 2BPQ 3QR9 4N5V 4N93 |
Descriptor | Anthranilate phosphoribosyltransferase, 2-amino-4-fluorobenzoic acid (3 entities in total) |
Functional Keywords | anthranilate phosphoribosyltransferase, anthranilic acids, magnesium, tryptophan, inhibitor, transferase, magnesium binding phosphoribosyl pyrophosphate |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 77891.95 |
Authors | Castell, A.,Cookson, T.V.M.,Bulloch, E.,Evans, G.L.,Baker, E.N.,Lott, J.S.,Parker, E.J. (deposition date: 2013-10-17, release date: 2014-04-23, Last modification date: 2023-09-20) |
Primary citation | Cookson, T.V.,Castell, A.,Bulloch, E.M.,Evans, G.L.,Short, F.L.,Baker, E.N.,Lott, J.S.,Parker, E.J. Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461:87-98, 2014 Cited by PubMed: 24712732DOI: 10.1042/BJ20140209 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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