4N7H

Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3

Summary for 4N7H

• Entry DOI: 10.2210/pdb4n7h/pdb
• Related: 4N7F
• Descriptor: E3 ubiquitin-protein ligase NEDD4, Arrestin domain-containing protein 3, GUANIDINE, ... (4 entities in total)
• Functional Keywords: ww domain, beta sheet, ppxy motif, protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (By similarity): P46934; Cytoplasm: Q96B67
• Total number of polymer chains: 2
• Total formula weight: 5796.45

Authors

Qi, S.,O'Hayre, M.,Gutkind, J.S.,Hurley, J. (deposition date: 2013-10-15, release date: 2014-01-08, Last modification date: 2024-02-28)

• Primary citation: Qi, S.,O'Hayre, M.,Gutkind, J.S.,Hurley, J.H.; Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).; J.Biol.Chem., 289:4743-4752, 2014; PubMed: 24379409; DOI: 10.1074/jbc.M113.527473

Experimental method

X-RAY DIFFRACTION (1.698 Å)