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4N7H

Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase NEDD4polymer374261.81UniProt (P46934)
Pfam (PF00397)
Homo sapiens (human)Cell proliferation-inducing gene 53 protein, Neural precursor cell expressed developmentally down-regulated protein 4, NEDD-4
2B
(B)
Arrestin domain-containing protein 3polymer131416.61UniProt (Q96B67)Homo sapiensTBP-2-like inducible membrane protein, TLIMP
3C, D
(A)
GUANIDINEnon-polymer59.12Chemie (GAI)
4E, F
(A, B)
waterwater18.031Chemie (HOH)
Sequence modifications
A: 421 - 453 (UniProt: P46934)
PDBExternal DatabaseDetails
Ala 417-expression tag
Met 418-expression tag
Gly 419-expression tag
Ser 420-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight5678.3
Non-Polymers*Number of molecules2
Total formula weight118.1
All*Total formula weight5796.5
*Water molecules are not included.

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PDB entries from 2024-12-25

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