4N6X
Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1
Summary for 4N6X
Entry DOI | 10.2210/pdb4n6x/pdb |
Descriptor | Na(+)/H(+) exchange regulatory cofactor NHE-RF1/Chemokine Receptor CXCR2 fusion protein, CHLORIDE ION (3 entities in total) |
Functional Keywords | cxcr2, nherf1, neutrophil, inflammatory diseases, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): O14745 |
Total number of polymer chains | 1 |
Total formula weight | 10002.13 |
Authors | Lu, G.,Wu, Y.,Jiang, Y.,Brunzelle, J.,Sirinupong, N.,Li, C.,Yang, Z. (deposition date: 2013-10-14, release date: 2014-01-15, Last modification date: 2024-02-28) |
Primary citation | Jiang, Y.,Lu, G.,Trescott, L.R.,Hou, Y.,Guan, X.,Wang, S.,Stamenkovich, A.,Brunzelle, J.,Sirinupong, N.,Li, C.,Yang, Z. New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping. Plos One, 8:e81904-e81904, 2013 Cited by PubMed: 24339979DOI: 10.1371/journal.pone.0081904 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.051 Å) |
Structure validation
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