4N6X

Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1

4N6X の概要

• エントリーDOI: 10.2210/pdb4n6x/pdb
• 分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF1/Chemokine Receptor CXCR2 fusion protein, CHLORIDE ION (3 entities in total)
• 機能のキーワード: cxcr2, nherf1, neutrophil, inflammatory diseases, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm (By similarity): O14745
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10002.13

構造登録者

Lu, G.,Wu, Y.,Jiang, Y.,Brunzelle, J.,Sirinupong, N.,Li, C.,Yang, Z. (登録日: 2013-10-14, 公開日: 2014-01-15, 最終更新日: 2024-02-28)

• 主引用文献: Jiang, Y.,Lu, G.,Trescott, L.R.,Hou, Y.,Guan, X.,Wang, S.,Stamenkovich, A.,Brunzelle, J.,Sirinupong, N.,Li, C.,Yang, Z.; New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping.; Plos One, 8:e81904-e81904, 2013; PubMed: 24339979; DOI: 10.1371/journal.pone.0081904

実験手法

X-RAY DIFFRACTION (1.051 Å)