4N12
Crystal structure of human E18D DJ-1 in complex with Cu
Summary for 4N12
Entry DOI | 10.2210/pdb4n12/pdb |
Related | 4MNT 4N0M |
Descriptor | Protein DJ-1, COPPER (II) ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | alpha/beta structure, chaperone, oxidative stress protection, cytosol, nucleus, mitochondria, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor: Q99497 |
Total number of polymer chains | 1 |
Total formula weight | 20060.64 |
Authors | Cendron, L.,Girotto, S.,Bisaglia, M.,Tessari, I.,Mammi, S.,Zanotti, G.,Bubacco, L. (deposition date: 2013-10-03, release date: 2014-03-05, Last modification date: 2014-11-12) |
Primary citation | Girotto, S.,Cendron, L.,Bisaglia, M.,Tessari, I.,Mammi, S.,Zanotti, G.,Bubacco, L. DJ-1 Is a Copper Chaperone Acting on SOD1 Activation. J.Biol.Chem., 289:10887-10899, 2014 Cited by PubMed: 24567322DOI: 10.1074/jbc.M113.535112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.478 Å) |
Structure validation
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