4MXP

Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM

4MXP の概要

• エントリーDOI: 10.2210/pdb4mxp/pdb
• 分子名称: Defects in Rab1 recruitment protein A, (2R)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: protein-lipid complex, guanine nucleotide exchange factor, rab1 binding, pi(4)p-binding protein
• 由来する生物種: Legionella pneumophila subsp. pneumophila
• 細胞内の位置: Secreted: Q5ZSQ3
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37691.56

構造登録者

Del Campo, C.M.,Mishra, A.K.,Wang, Y.H.,Roy, C.R.,Janmey, P.A.,Lambright, D.G. (登録日: 2013-09-26, 公開日: 2014-03-19, 最終更新日: 2023-09-20)

• 主引用文献: Del Campo, C.M.,Mishra, A.K.,Wang, Y.H.,Roy, C.R.,Janmey, P.A.,Lambright, D.G.; Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM.; Structure, 22:397-408, 2014; PubMed: 24530282; DOI: 10.1016/j.str.2013.12.018

実験手法

X-RAY DIFFRACTION (1.83 Å)