4MXE

Human ESCO1 (Eco1/Ctf7 ortholog), acetyltransferase domain in complex with acetyl-CoA

Summary for 4MXE

• Entry DOI: 10.2210/pdb4mxe/pdb
• Descriptor: N-acetyltransferase ESCO1, ACETYL COENZYME *A (3 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, gcn5-related n-acetyltransferase fold, acetyltransferase, nucleus, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q5FWF5
• Total number of polymer chains: 2
• Total formula weight: 49616.83

Authors

Karlberg, T.,Wisniewska, M.,Thorsell, A.G.,Kouznetsova, E.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kraulis, P.,Kotenyova, T.,Moche, M.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Persson, C.,Schutz, P.,Svensson, L.,Tresaugues, L.,Van Den Berg, S.,Wahlberg, E.,Weigelt, J.,Welin, M.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2013-09-26, release date: 2015-04-08, Last modification date: 2016-05-18)

• Primary citation: Kouznetsova, E.,Kanno, T.,Karlberg, T.,Thorsell, A.G.,Wisniewska, M.,Kursula, P.,Sjogren, C.,Schuler, H.; Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis.; Structure, 24:789-796, 2016; PubMed: 27112597; DOI: 10.1016/j.str.2016.03.021

Experimental method

X-RAY DIFFRACTION (2.6 Å)