4MSV

Crystal structure of FASL and DcR3 complex

4MSV の概要

• エントリーDOI: 10.2210/pdb4msv/pdb
• 関連するPDBエントリー: 3K51 3MHD 4EN0 4J6G 4KGG 4KGQ
• 分子名称: Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 6, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: fasl, dcr3, tnf, tnfr, tnf6, structural genomics, psi-biology, new york structural genomics, research consortium, nysgrc, immunity, tnf supe cd95l, fas ligand, membrane, atoms-to-animals: the immune function network, ifn, jelly-roll fold, bind tnf receptor fas, protein structure initiative, new york structural genomics research consortium, cd95l, tnf superfamily, secreted protein, cytokine, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type II membrane protein. Tumor necrosis factor ligand superfamily member 6, soluble form: Secreted . FasL intracellular domain: Nucleus: O95407; Secreted: P48023
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36505.57

構造登録者

Liu, W.,Ramagopal, U.A.,Zhan, C.,Bonanno, J.B.,Bhosle, R.C.,Nathenson, S.G.,Almo, S.C.,Atoms-to-Animals: The Immune Function Network (IFN),New York Structural Genomics Research Consortium (NYSGRC) (登録日: 2013-09-18, 公開日: 2013-11-27, 最終更新日: 2023-09-20)

• 主引用文献: Liu, W.,Ramagopal, U.,Cheng, H.,Bonanno, J.B.,Toro, R.,Bhosle, R.,Zhan, C.,Almo, S.C.; Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.; Structure, 24:2016-2023, 2016; PubMed: 27806260; DOI: 10.1016/j.str.2016.09.009

実験手法

X-RAY DIFFRACTION (2.5 Å)