4MSM

Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 E286A mutant bound to ubiquitin

4MSM の概要

• エントリーDOI: 10.2210/pdb4msm/pdb
• 関連するPDBエントリー: 3RZU 4JXE 4MS7 4MSD 4MSJ 4MSQ
• 分子名称: AMSH-like protease sst2, Ubiquitin, ZINC ION, ... (6 entities in total)
• 機能のキーワード: helix-beta-helix sandwich, ubiquitin, deubiquitination, zinc metalloprotease, lysine 63-linked polyubiquitin, cytosol, endosome, hydrolase-protein binding complex, hydrolase/protein binding
• 由来する生物種: Schizosaccharomyces pombe (Fission yeast); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 62896.22

構造登録者

Shrestha, R.K.,Ronau, J.A.,Das, C. (登録日: 2013-09-18, 公開日: 2014-06-18, 最終更新日: 2023-09-20)

• 主引用文献: Shrestha, R.K.,Ronau, J.A.,Davies, C.W.,Guenette, R.G.,Strieter, E.R.,Paul, L.N.,Das, C.; Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.; Biochemistry, 53:3199-3217, 2014; PubMed: 24787148; DOI: 10.1021/bi5003162

実験手法

X-RAY DIFFRACTION (1.74 Å)