Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| A | 0061578 | molecular_function | K63-linked deubiquitinase activity |
| A | 0070536 | biological_process | protein K63-linked deubiquitination |
| A | 0140492 | molecular_function | metal-dependent deubiquitinase activity |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0008237 | molecular_function | metallopeptidase activity |
| C | 0016579 | biological_process | protein deubiquitination |
| C | 0061578 | molecular_function | K63-linked deubiquitinase activity |
| C | 0070536 | biological_process | protein K63-linked deubiquitination |
| C | 0140492 | molecular_function | metal-dependent deubiquitinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 501 |
| Chain | Residue |
| A | HIS341 |
| A | HIS343 |
| A | ASP354 |
| A | HOH694 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 502 |
| Chain | Residue |
| A | HIS356 |
| A | CYS397 |
| A | HIS404 |
| A | HIS406 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 503 |
| Chain | Residue |
| A | HOH604 |
| B | THR9 |
| A | ARG261 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 504 |
| Chain | Residue |
| A | HIS356 |
| A | CYS359 |
| A | SER360 |
| A | HOH627 |
| A | HOH692 |
| A | HOH718 |
| B | PRO37 |
| B | GLN40 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 505 |
| Chain | Residue |
| A | LYS409 |
| A | THR412 |
| A | MET413 |
| A | HOH657 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 101 |
| Chain | Residue |
| A | HOH603 |
| B | THR7 |
| B | LEU8 |
| B | LEU69 |
| B | VAL70 |
| B | LEU71 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 102 |
| Chain | Residue |
| B | ARG54 |
| C | LYS409 |
| C | TYR411 |
| C | PO4508 |
| C | HOH612 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 501 |
| Chain | Residue |
| C | HIS341 |
| C | HIS343 |
| C | ASP354 |
| D | HOH240 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 502 |
| Chain | Residue |
| C | HIS356 |
| C | CYS397 |
| C | HIS404 |
| C | HIS406 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 503 |
| Chain | Residue |
| C | LEU274 |
| C | PRO375 |
| C | HOH672 |
| C | HOH702 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO C 504 |
| Chain | Residue |
| C | LYS294 |
| C | PO4508 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 505 |
| Chain | Residue |
| C | LYS258 |
| C | GLN362 |
| C | LEU363 |
| C | PRO366 |
| C | ASP387 |
| C | HOH693 |
| C | HOH713 |
| C | HOH715 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 506 |
| Chain | Residue |
| C | HIS356 |
| C | CYS397 |
| C | ARG398 |
| C | LYS399 |
| C | HIS404 |
| C | HOH709 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 507 |
| Chain | Residue |
| C | GLU311 |
| C | GLY318 |
| C | THR319 |
| C | THR320 |
| C | HOH699 |
| D | ARG74 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 C 508 |
| Chain | Residue |
| B | EDO102 |
| C | LYS409 |
| C | THR412 |
| C | MET413 |
| C | EDO504 |
| C | HOH626 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 101 |
| Chain | Residue |
| C | HOH604 |
| D | THR7 |
| D | LEU8 |
| D | LEU69 |
| D | VAL70 |
| D | LEU71 |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| B | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 260 |
| Details | Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 26 |
| Details | Motif: {"description":"JAMM motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Indirect zinc-binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 150 |
| Details | Domain: {"description":"Ubiquitin-like 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]} |
