4MP0
Structure of a second nuclear PP1 Holoenzyme, crystal form 2
Summary for 4MP0
Entry DOI | 10.2210/pdb4mp0/pdb |
Related | 3V4Y 4MOY |
Descriptor | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, Serine/threonine-protein phosphatase 1 regulatory subunit 10, MANGANESE (II) ION, ... (6 entities in total) |
Functional Keywords | serine/threonine phosphatase, nucleus, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P62136 Nucleus (By similarity): O55000 |
Total number of polymer chains | 4 |
Total formula weight | 79355.92 |
Authors | Choy, M.S.,Hieke, M.,Peti, W.,Page, R. (deposition date: 2013-09-12, release date: 2014-03-26, Last modification date: 2024-02-28) |
Primary citation | Choy, M.S.,Hieke, M.,Kumar, G.S.,Lewis, G.R.,Gonzalez-Dewhitt, K.R.,Kessler, R.P.,Stein, B.J.,Hessenberger, M.,Nairn, A.C.,Peti, W.,Page, R. Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code. Proc.Natl.Acad.Sci.USA, 111:4097-4102, 2014 Cited by PubMed: 24591642DOI: 10.1073/pnas.1317395111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1003 Å) |
Structure validation
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