Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4MMV

Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5

Summary for 4MMV
Entry DOI10.2210/pdb4mmv/pdb
Related4JHW 4MMQ 4MMR 4MMS 4MMT 4MMU
DescriptorFusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain (3 entities in total)
Functional Keywordsfusion, membrane, viral protein, structure-based vaccine design
Biological sourceHuman respiratory syncytial virus A2
More
Cellular locationVirion membrane; Single-pass type I membrane protein: P03420
Virion : P10104
Total number of polymer chains2
Total formula weight54908.73
Authors
Stewart-Jones, G.B.E.,McLellan, J.S.,Joyce, M.G.,Sastry, M.,Yang, Y.,Graham, B.S.,Kwong, P.D. (deposition date: 2013-09-09, release date: 2013-11-20, Last modification date: 2021-06-02)
Primary citationMcLellan, J.S.,Chen, M.,Joyce, M.G.,Sastry, M.,Stewart-Jones, G.B.,Yang, Y.,Zhang, B.,Chen, L.,Srivatsan, S.,Zheng, A.,Zhou, T.,Graepel, K.W.,Kumar, A.,Moin, S.,Boyington, J.C.,Chuang, G.Y.,Soto, C.,Baxa, U.,Bakker, A.Q.,Spits, H.,Beaumont, T.,Zheng, Z.,Xia, N.,Ko, S.Y.,Todd, J.P.,Rao, S.,Graham, B.S.,Kwong, P.D.
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342:592-598, 2013
Cited by
PubMed: 24179220
DOI: 10.1126/science.1243283
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.81 Å)
Structure validation

217705

数据于2024-03-27公开中

PDB statisticsPDBj update infoContact PDBjnumon