4MM5

Crystal structure of LeuBAT (delta13 mutant) in complex with sertraline

Summary for 4MM5

Entry DOI	10.2210/pdb4mm5/pdb
Related	4MM4 4MM6 4MM7 4MM8 4MM9 4MMA 4MMB 4MMC 4MMD 4MME 4MMF
Descriptor	Transporter, SODIUM ION, (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, ... (4 entities in total)
Functional Keywords	transporter, transport protein
Biological source	Aquifex aeolicus
Total number of polymer chains	1
Total formula weight	58340.48
Authors	Wang, H.,Gouaux, E. (deposition date: 2013-09-08, release date: 2013-10-16, Last modification date: 2024-02-28)
Primary citation	Wang, H.,Goehring, A.,Wang, K.H.,Penmatsa, A.,Ressler, R.,Gouaux, E. Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503:141-145, 2013 Cited by PubMed: 24121440 DOI: 10.1038/nature12648 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation