4MM3
Crystal structure of SARS-CoV papain-like protease PLpro in complex with ubiquitin aldehyde
4MM3 の概要
エントリーDOI | 10.2210/pdb4mm3/pdb |
関連するPDBエントリー | 1UBQ 2FE8 |
分子名称 | Ubiquitin, Papain-like proteinase, ZINC ION, ... (4 entities in total) |
機能のキーワード | nsp3 papain-like protease domain, signaling protein-hydrolase complex, signaling protein/hydrolase |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Ubiquitin: Cytoplasm : P0CG48 Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region : P0C6U8 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 44146.51 |
構造登録者 | |
主引用文献 | Ratia, K.,Kilianski, A.,Baez-Santos, Y.M.,Baker, S.C.,Mesecar, A. Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease. Plos Pathog., 10:e1004113-e1004113, 2014 Cited by PubMed: 24854014DOI: 10.1371/journal.ppat.1004113 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.752 Å) |
構造検証レポート
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