4MLV

Crystal Structure of Bacillus megaterium porphobilinogen deaminase

4MLV の概要

• エントリーDOI: 10.2210/pdb4mlv/pdb
• 関連するPDBエントリー: 1PDA 4HTG
• 分子名称: Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, 3-[(5S)-5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]propanoic acid, ... (5 entities in total)
• 機能のキーワード: tetrapyrrole biosynthesis, porphobilinogen deaminase, dipyrromethane cofactor, three-domain fold, domains 1 and 2 resemble the fold of type ii periplasmic binding proteins, pyrrole polymerisation, transferase
• 由来する生物種: Bacillus megaterium
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35429.65

構造登録者

Azim, N.,Deery, E.,Warren, M.J.,Erskine, P.,Cooper, J.B.,Coker, A.,Wood, S.P.,Akhtar, M. (登録日: 2013-09-06, 公開日: 2014-04-02, 最終更新日: 2023-09-20)

• 主引用文献: Azim, N.,Deery, E.,Warren, M.J.,Wolfenden, B.A.,Erskine, P.,Cooper, J.B.,Coker, A.,Wood, S.P.,Akhtar, M.; Structural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of the Bacillus megaterium enzyme at near-atomic resolution.; Acta Crystallogr.,Sect.D, 70:744-751, 2014; PubMed: 24598743; DOI: 10.1107/S139900471303294X

実験手法

X-RAY DIFFRACTION (1.455 Å)