4MLN

Crystal of PhnZ bound to (R)-2-amino-1-hydroxyethylphosphonic acid

Summary for 4MLN

Entry DOI	10.2210/pdb4mln/pdb
Related	4MLM
Descriptor	Predicted HD phosphohydrolase PhnZ, FE (III) ION, [(1R)-2-amino-1-hydroxyethyl]phosphonic acid, ... (4 entities in total)
Functional Keywords	structural genomics, montreal-kingston bacterial structural genomics initiative, bsgi, all alpha, carbon-phosphorus bond cleavage, hydrolase
Biological source	uncultured bacterium HF130_AEPn_1
Total number of polymer chains	2
Total formula weight	45397.77
Authors	van Staalduinen, L.M.,McSorley, F.R.,Zechel, D.L.,Jia, Z.,Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) (deposition date: 2013-09-06, release date: 2014-04-16, Last modification date: 2023-09-20)
Primary citation	van Staalduinen, L.M.,McSorley, F.R.,Schiessl, K.,Seguin, J.,Wyatt, P.B.,Hammerschmidt, F.,Zechel, D.L.,Jia, Z. Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates. Proc.Natl.Acad.Sci.USA, 111:5171-5176, 2014 Cited by PubMed: 24706911 DOI: 10.1073/pnas.1320039111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation