4MJI
T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01
Summary for 4MJI
Entry DOI | 10.2210/pdb4mji/pdb |
Descriptor | HLA class I histocompatibility antigen, B-51 alpha chain, Beta-2-microglobulin, HIV Reverse Transcriptase peptide Marker, ... (5 entities in total) |
Functional Keywords | hiv, peptide-major histocompatibility complex, pmhc, surface plasmon resonance, spr, t-cell, t-cell receptor, tcr, immunoglobulin, class i mhc, antigen presentation, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P18464 Secreted: P61769 |
Total number of polymer chains | 10 |
Total formula weight | 186354.04 |
Authors | Rizkallah, P.J.,Cole, D.K.,Sewell, A.K.,Motozono, C.,Takiguchi, M. (deposition date: 2013-09-03, release date: 2014-05-28) |
Primary citation | Motozono, C.,Kuse, N.,Sun, X.,Rizkallah, P.J.,Fuller, A.,Oka, S.,Cole, D.K.,Sewell, A.K.,Takiguchi, M. Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01 J.Immunol., 192:3428-3434, 2014 Cited by PubMed: 24600035DOI: 10.4049/jimmunol.1302667 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.99 Å) |
Structure validation
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