4MIV

Crystal Structure of Sulfamidase, Crystal Form L

Summary for 4MIV

• Entry DOI: 10.2210/pdb4miv/pdb
• Related: 4MHX
• Descriptor: N-sulphoglucosamine sulphohydrolase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total)
• Functional Keywords: sulfatase fold, heparan, heparin, lysosome, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Lysosome: P51688
• Total number of polymer chains: 8
• Total formula weight: 473849.73

Authors

Sidhu, N.S.,Uson, I.,Schreiber, K.,Proepper, K.,Becker, S.,Sheldrick, G.M.,Gaertner, J.,Kraetzner, R.,Steinfeld, R. (deposition date: 2013-09-02, release date: 2014-05-14, Last modification date: 2021-06-02)

• Primary citation: Sidhu, N.S.,Schreiber, K.,Propper, K.,Becker, S.,Uson, I.,Sheldrick, G.M.,Gartner, J.,Kratzner, R.,Steinfeld, R.; Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA.; Acta Crystallogr.,Sect.D, 70:1321-1335, 2014; PubMed: 24816101; DOI: 10.1107/S1399004714002739

Experimental method

X-RAY DIFFRACTION (2.4 Å)