4MID

Crystal Structure of Activin A/BMP2 chimera

Summary for 4MID

Entry DOI	10.2210/pdb4mid/pdb
Descriptor	AB204 Activin A/BMP2 chimera (2 entities in total)
Functional Keywords	cysteine knot, cytokine, actrii, bmpria, secreted
Biological source	Homo sapiens
Total number of polymer chains	1
Total formula weight	13090.08
Authors	Esquivies, L. (deposition date: 2013-08-30, release date: 2014-05-07, Last modification date: 2019-07-17)
Primary citation	Yoon, B.H.,Esquivies, L.,Ahn, C.,Gray, P.C.,Ye, S.K.,Kwiatkowski, W.,Choe, S. An Activin A/BMP2 Chimera, AB204, Displays Bone-Healing Properties Superior to Those of BMP2. J.Bone Miner.Res., 29:1950-1959, 2014 Cited by PubMed: 24692083 DOI: 10.1002/jbmr.2238 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.139 Å)

Structure validation