4MI5
Crystal structure of the EZH2 SET domain
Summary for 4MI5
Entry DOI | 10.2210/pdb4mi5/pdb |
Descriptor | Histone-lysine N-methyltransferase EZH2, SULFATE ION, ZINC ION, ... (4 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q15910 |
Total number of polymer chains | 1 |
Total formula weight | 26460.17 |
Authors | Antonysamy, S.,Condon, B.,Druzina, Z.,Bonanno, J.,Gheyi, T.,Macewan, I.,Zhang, A.,Ashok, S.,Russell, M.,Luz, J.G. (deposition date: 2013-08-30, release date: 2014-01-08, Last modification date: 2024-02-28) |
Primary citation | Antonysamy, S.,Condon, B.,Druzina, Z.,Bonanno, J.B.,Gheyi, T.,Zhang, F.,Macewan, I.,Zhang, A.,Ashok, S.,Rodgers, L.,Russell, M.,Gately Luz, J. Structural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET Domain. Plos One, 8:e84147-e84147, 2013 Cited by PubMed: 24367637DOI: 10.1371/journal.pone.0084147 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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