4MI5

Crystal structure of the EZH2 SET domain

4MI5 の概要

分子名称Histone-lysine N-methyltransferase EZH2, SULFATE ION, ZINC ION, ... (4 entities in total)
機能のキーワードtransferase
由来する生物種Homo sapiens (human)
細胞内の位置Nucleus Q15910
ポリマー鎖数1
分子量合計26460.17
構造登録者
主引用文献
Antonysamy, S.,Condon, B.,Druzina, Z.,Bonanno, J.B.,Gheyi, T.,Zhang, F.,Macewan, I.,Zhang, A.,Ashok, S.,Rodgers, L.,Russell, M.,Gately Luz, J.
Structural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET Domain.
Plos One, 8:e84147-e84147, 2013
PubMed: 24367637 (主引用文献が同じPDBエントリー)
DOI: 10.1371/journal.pone.0084147
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25830.5%1.2%3.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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