4MGV
Crystal structure of FK506 binding domain of plasmodium VIVAX FKBP35 In complex with inhibitor D5
Summary for 4MGV
Entry DOI | 10.2210/pdb4mgv/pdb |
Related | 3IHZ 4ITZ 4J4N 4J4O |
Descriptor | 70 kDa peptidylprolyl isomerase, putative, N'-(1-adamantylcarbonyl)pyridine-4-carbohydrazide (3 entities in total) |
Functional Keywords | inhibitor, d5, fkbp, fkbp35, isomerase, fk506 |
Biological source | Plasmodium vivax |
Total number of polymer chains | 1 |
Total formula weight | 14271.06 |
Authors | Rajan, S.,Harikishore, A.,Yoon, H.S. (deposition date: 2013-08-29, release date: 2013-12-04, Last modification date: 2023-11-08) |
Primary citation | Harikishore, A.,Leow, M.L.,Niang, M.,Rajan, S.,Pasunooti, K.K.,Preiser, P.R.,Liu, X.,Yoon, H.S. Adamantyl derivative as a potent inhibitor of Plasmodium FK506 binding protein 35. Acs Med.Chem.Lett., 4:1097-1101, 2013 Cited by PubMed: 24900611DOI: 10.1021/ml400306r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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