4M92

Crystal structure of hN33/Tusc3-peptide 2

Summary for 4M92

Entry DOI	10.2210/pdb4m92/pdb
Related	4M8G 4M90 4M91
Descriptor	Tumor suppressor candidate 3, Interleukin-1 receptor accessory protein-like 1 (3 entities in total)
Functional Keywords	thioredoxin-like fold; thiol/disulfide oxidoreductase; thiol/disulfide exchange reactions; redox-active protein; oxidoreductase, oxidoreductase
Biological source	Homo sapiens (human) More
Cellular location	Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity): Q13454 Cell membrane; Single-pass type I membrane protein: Q9NZN1
Total number of polymer chains	2
Total formula weight	20960.76
Authors	Mohorko, E.,Owen, R.L.,Malojcic, G.,Brozzo, M.S.,Aebi, M.,Glockshuber, R. (deposition date: 2013-08-14, release date: 2014-03-26, Last modification date: 2023-09-20)
Primary citation	Mohorko, E.,Owen, R.L.,Malojcic, G.,Brozzo, M.S.,Aebi, M.,Glockshuber, R. Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation. Structure, 22:590-601, 2014 Cited by PubMed: 24685145 DOI: 10.1016/j.str.2014.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation