4M81

The structure of E292S glycosynthase variant of exo-1,3-beta-glucanase from Candida albicans complexed with 1-fluoro-alpha-D-glucopyranoside (donor) and p-nitrophenyl beta-D-glucopyranoside (acceptor) at 1.86A resolution

4M81 の概要

• エントリーDOI: 10.2210/pdb4m81/pdb
• 関連するPDBエントリー: 1CZ1 4M80 4M82
• 分子名称: EXO-1,3-BETA-GLUCANASE, alpha-D-glucopyranosyl fluoride, 4-nitrophenyl beta-D-glucopyranoside, ... (5 entities in total)
• 機能のキーワード: tim barrel, glycoside hydrolase family 5, glycoside hydrolase, cell wall hydrolase, glycosynthase, hydrolase, protein-carbohydrate interaction
• 由来する生物種: Candida albicans (yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46268.80

構造登録者

Nakatani, Y.,Cutfield, S.M.,Larsen, D.S.,Cutfield, J.F. (登録日: 2013-08-12, 公開日: 2014-06-25, 最終更新日: 2023-09-20)

• 主引用文献: Nakatani, Y.,Larsen, D.S.,Cutfield, S.M.,Cutfield, J.F.; Major Change in Regiospecificity for the Exo-1,3-beta-glucanase from Candida albicans following Its Conversion to a Glycosynthase.; Biochemistry, 53:3318-3326, 2014; PubMed: 24804868; DOI: 10.1021/bi500239m

実験手法

X-RAY DIFFRACTION (1.86 Å)