4M76

Integrin I domain of complement receptor 3 in complex with C3d

4M76 の概要

• エントリーDOI: 10.2210/pdb4m76/pdb
• 分子名称: Complement C3, Integrin alpha-M, NICKEL (II) ION, ... (4 entities in total)
• 機能のキーワード: integrin, complement receptor, immunity, innate immunity, inflammation, phagocytosis, mac-1, cd11b/cd18, alphambeta2, macrophage, rossmann fold, i domain, von willebrand factor a (vwa), alpha-alpha barrel, adhesion, cell adhesion
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01024; Membrane; Single-pass type I membrane protein: P11215
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55796.98

構造登録者

Bajic, G.,Yatime, L.,Vorup-Jensen, T.,Andersen, G.R. (登録日: 2013-08-12, 公開日: 2013-10-02, 最終更新日: 2023-09-20)

• 主引用文献: Bajic, G.,Yatime, L.,Sim, R.B.,Vorup-Jensen, T.,Andersen, G.R.; Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3.; Proc.Natl.Acad.Sci.USA, 110:16426-16431, 2013; PubMed: 24065820; DOI: 10.1073/pnas.1311261110

実験手法

X-RAY DIFFRACTION (2.804 Å)